癌痛有多痛？没疼过的人永远不知道。癌症相关疼痛是肿瘤患者最常见却又最难控制的症状之一。几乎可以让任何意志坚强的人屈服。痛不欲生的感觉让很多患者自愿放弃生命。 据世界卫生组织(WHO)统计，全世界每年有1000万新发癌症患者，600万人死于癌症，其中50%的患者有癌性疼痛症状。癌痛作为一个世界性难题，每天都在影响无数癌症患者的生活。大约70%的晚期癌症患者以疼痛为主要症状。在疼痛患者中，因各种原因使50%～80%的疼痛没有得到有效控制。当前，中国每年新发癌症患者数约160-180万，每年死于癌症的人数达到140万。研究表明，中国癌性疼痛病人发病率高达50%左右，疼痛的原因以肿瘤直接引起的疼痛占第1位约占80%，同时治疗肿瘤也可引起疼痛，发生率占10%左右。其他10%为与肿瘤相关或无关原因。 Cancer-related pain (CRP) is one of the most common and symptoms associated with cancer progression and treatment.
癌症相关疼痛(CRP)是与癌症进展和治疗相关的最常见和最衰弱（debilitating）的症状之一。
Affecting approximately half of patients with cancer, CRP has significant implications for the quality of life (QOL), psychosocial well-being, and daily functioning of patients with cancer and cancer survivors.
CRP can be caused by a number of factors associated with cancer and, depending on the cause, may manifest in different forms and at varying severities.
CRP可以由许多与癌症相关的因素引起，根据原因的不同，可能以不同的形式和不同的严重程度表现出来【2】。
Appropriate treatment of CRP should be individualized and comprehensive, and should account for patient preferences.
CRP的适当治疗应个体化和全面，并应考虑患者的偏好【3】。
Frequently explored by patients with CRP, complementary and alternative medicine (CAM) serves as a potential option for relief.
CRP患者经常探索，补充和替代药物(CAM)作为一种潜在的缓解选择【3】。
Complementary medicine is the use of non-mainstream treatments in addition to conventional treatment, while alternative medicine involves the use of non-mainstream treatment instead of conventional treatment.
Results of the 2007 National Health Interview Survey indicated that 65% of American respondents who had ever received a cancer diagnosis reported using CAM approaches at some point.
2007年全国健康访谈调查的结果显示，65%曾接受过癌症诊断的美国受访者曾在某个时候报告使用过CAM方法【5 】。
In a separate study, CAM use was reported by 40% to 85% of patients with cancer.
在另一项研究中，40%至85%的癌症患者报告使用CAM【6】。
In a study investigating the prevalence of CAM use by women with breast cancer, 58% of respondents reported having used CAM specifically to relieve symptoms of their cancer or its treatment,7 among the most prevalent of which was CRP.
在一项调查乳腺癌女性使用CAM流行率的研究中，58%的受访者报告曾专门使用CAM来缓解癌症症状或其治疗，其中最流行的是CRP【8】。
Several CAM therapies have been proposed for the management of symptoms associated with cancer, such as CRP.
一些CAM疗法已经被提出用于管理与癌症相关的症状，包括CRP。
These therapies include hypnosis, relaxation therapy, acupuncture, massage, and yoga.
Evidence suggests that massage in particular can help relieve cancer-related pain.
有证据表明，按摩尤其可以帮助缓解与癌症相关的疼痛【5】。
Hypnosis, acupuncture, imagery, and support groups show promising clinical benefits for CRP, though more rigorous trials of these interventions in a CRP context are lacking.
This knowledge gap is further compounded by the fact that clinicians involved in treating CRP rarely receive sufficient training in the use of CAM therapies.
参与治疗CRP的临床医生很少在使用CAM治疗方面接受足够的培训，这进一步加剧了这一知识差距【11】。
Healthcare professionals rely on evidence-based CPGs to make recommendations associated with the management of CRP.
医疗保健专业人员依赖于循证CPGs来提出与CRP管理相关的建议。
Due to a lack of relevant clinician training and knowledge about the use of CAM therapies for CRP,【11 12 13】 evidence-based CPGs on CRP treatment are a particularly valuable tool for healthcare professionals involved in CRP treatment.
The present study has identified and summarized a number of CPGs that clinicians may consult to understand what CAMs are recommended in the context of the treatment and/or management of CRP.
本栏目确定并总结了一些临床医生可以咨询的CPGs，以了解在CRP的治疗和/或管理中推荐的CAMs。
To date, an appraisal of CPGs for CRP including CAM recommendations has not been conducted.
到目前为止，尚未对CRP的CPG进行评估，包括CAM的建议。
As a result, no thorough evaluation of the credibility of CAM recommendations for cancer pain CPGs is available.
因此，目前没有关于CAM建议对癌症疼痛CPGs的可信度的彻底评估。
The purpose of this systematic review was to characterize and define mentions of CAM in cancer pain CPGs, and to assess the quality of CAM recommendations using the Appraisal of Guidelines, Research and Evaluation II (AGREE II) instrument.
本栏目的目的是描述和定义癌症疼痛CPGs中CAM的提及，并使用指南评估、研究和评估II(Agree II)工具来评估CAM建议的质量。
This review is meant to provide an assessment and summary of existing CPGs for CAM treatment of CRP.
本栏目旨在对CAM治疗CRP的现有cpg进行评估和总结。
These findings may serve to aid clinicians in symptom management and patient counseling during interactions with patients with CRP seeking or using CAM.
这些发现可能有助于帮助临床医生在与寻求或使用CAM的CRP患者互动时进行症状管理和患者咨询。
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