CT /CT fluoroscopic guidance 6 MWA systems utilized Conscious sedation (midazolam and fentanyl) and local anesthesia (buffered lidocaine) routinely used No patients required general anesthesia Continues EKG and pulse oximetry, blood pressu...

Exclusion Criteria Imaging or histologic evidence of nodal disease Tumors abutting （毗连）mediastinal structures, large hilar vessels, or mainstem bronchi（支气管主干） INR greater than 1.8...

Microwave Ablation (MWA) Generates heat using oscillating electromagnetic wave of 300 MHz to 300 GHz Advantages Greater ablative temperatures and shorter treatment times No need for patient grounding pads（接地的垫） Improved heating radiu...

肺癌的治疗策略（treatment strategies） Early stage primary lung cancer/mets - Surgical resection - but many medically ineligible for surgery - recurrence after metastatectomy common - Radiotherapy - Image-guided thermal ablation early stag...

Primary lung cancer Most common cause of cancer-related mortality Diagnostic dilemma - shell we screen? - 20 % reduction of lung cancer mortality - Cost-effectiveness: up to $ 169000 per QUALY（www.cancerresearchuk.org） Therapeutic challe...

Evaluating Response mRECIST（肺癌的mRECIST标准） 注意此标准和肝癌TACE的mRECIST标准的不同 Complete response (CR) was where the target lesion demonstrated cavitations, necrosis and cyst formation with a 25% reduction in size Partial response...

肺癌经皮热消融少有技术失败的情况 Insert Technically Unsucc Case 肿瘤与肺动脉还有距离 在针的推力下，肿瘤接近肺动脉 肿瘤与肺动脉已经无距离...

Chan, Victoria O.; McDermott, Shaunagh; Malone, Dermot E.; Dodd, Jonathan D. Percutaneous Radiofrequency Ablation of Lung Tumors: Evaluation of the Literature Using Evidence-based Techniques。Journal of Thoracic Imaging. 26(1):18-26, Febru...

MWA shows technically a better predictabel thermal profile: larger, less variable (shape and size!) and more homogeneous (skip areas!) coagulations (higher vascular thrombosis rate!) clinically a more favourable setting/outcome: no ground...

RFA - Local efficacy Median time to local tumor progression Simon CJ et al., Pulmonary Radiofrequency Ablation: Long-Term Safety and Efficacy in 153 Patients 2007, Radiology...